What is Paxil®?

Paxil is an antidepressant drug belonging to a class of medications known as selective serotonin reuptake inhibitors (SSRIs). Paxil became available in the U.S. in 1993 and is manufactured by GlaxoSmithKline. It is used to treat Depression, Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Panic Disorder, and Obsessive Compulsive Disorder.

How Paxil® Works

Decreased levels of serotonin - a neurotransmitter that maintains positive emotions - in the brain contribute to depression. Paxil® works to treat depression by blocking the reabsorption of serotonin and correcting the chemical imbalance in the brain.

Dangers of Paxil®

Since Paxil® was introduced to consumers, various side effects have been associated with use of the medication.

Paxil® Use during Pregnancy

Two separate studies have found an increased risk of birth defects linked with Paxil® use. According to the studies, babies exposed to Paxil® during the first trimester of pregnancy have an increased risk of heart problems.

Paxil® Withdrawals

Individuals who have used Paxil® for an extended period of time have experienced withdrawals when they stopped using the medication. The withdrawal symptoms can include depression, suicidal thoughts, anxiety, and nausea.

Drug Interactions

Paxil® should not be taken in conjunction with monoamine oxidase inhibitors (MAOIs) such as Nardil, Parnate, Marplan, Eldepryl, and Aurorex - serious side effects such as extreme agitation, delirium, and coma can occur by mixing these two drugs. Patients should not take Paxil® while undergoing treatment with tryptophan - the combination can cause headaches, nausea, sweating, and dizziness. In addition, patients should consult with a physician before taking Paxil® with any of the following medications: Warfarin, Sumatriptan, Tricyclic Antidepressants (TCAs), and Lithium. Patients taking Paxil® should also avoid alcohol because of a potential for mental and motor impairment.

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